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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNJ4
All Species:
20.91
Human Site:
T345
Identified Species:
51.11
UniProt:
P48050
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48050
NP_004972.1
445
49500
T345
K
T
Y
E
V
A
G
T
P
C
C
S
A
R
E
Chimpanzee
Pan troglodytes
XP_001154349
535
59805
S445
N
Q
Y
K
I
D
Y
S
H
F
H
K
T
Y
E
Rhesus Macaque
Macaca mulatta
XP_001104273
433
48999
S343
N
Q
Y
K
I
D
Y
S
H
F
H
K
T
Y
E
Dog
Lupus familis
XP_538374
448
49729
T348
K
T
Y
E
V
A
G
T
P
C
C
S
A
R
E
Cat
Felis silvestris
Mouse
Mus musculus
P52189
445
49881
T344
K
T
Y
E
V
A
G
T
P
C
C
S
A
R
E
Rat
Rattus norvegicus
P52190
446
49672
T345
K
T
Y
E
V
A
G
T
P
C
C
S
A
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514007
449
50160
T345
K
T
Y
E
V
T
G
T
P
C
C
S
A
R
E
Chicken
Gallus gallus
P52186
427
48500
K338
F
E
E
K
N
Y
Y
K
V
D
Y
S
R
F
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_697604
437
49936
H346
Q
Y
K
V
D
Y
S
H
F
H
K
T
Y
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P52192
505
57401
N417
H
E
H
K
L
E
D
N
R
S
S
D
S
T
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.6
64.4
96.6
N.A.
97.3
97
N.A.
91
59.7
N.A.
64.2
N.A.
N.A.
N.A.
30.5
N.A.
Protein Similarity:
100
59.8
77
96.8
N.A.
97.9
97.3
N.A.
93.7
74.1
N.A.
74.6
N.A.
N.A.
N.A.
46.7
N.A.
P-Site Identity:
100
13.3
13.3
100
N.A.
100
100
N.A.
93.3
6.6
N.A.
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
33.3
33.3
100
N.A.
100
100
N.A.
93.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
40
0
0
0
0
0
0
50
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
50
50
0
0
0
0
% C
% Asp:
0
0
0
0
10
20
10
0
0
10
0
10
0
0
0
% D
% Glu:
0
20
10
50
0
10
0
0
0
0
0
0
0
10
70
% E
% Phe:
10
0
0
0
0
0
0
0
10
20
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
50
0
0
0
0
0
0
0
0
% G
% His:
10
0
10
0
0
0
0
10
20
10
20
0
0
0
10
% H
% Ile:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
50
0
10
40
0
0
0
10
0
0
10
20
0
0
0
% K
% Leu:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
20
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
10
% P
% Gln:
10
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
10
50
0
% R
% Ser:
0
0
0
0
0
0
10
20
0
10
10
60
10
0
0
% S
% Thr:
0
50
0
0
0
10
0
50
0
0
0
10
20
10
0
% T
% Val:
0
0
0
10
50
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
70
0
0
20
30
0
0
0
10
0
10
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _